Chances are (except in chemical imbalance situation) your spouse already know their area of short-coming or what they need to do to bring about change. Emphasizing those areas or using them as “jabbing” points during conflict would only exasperate your spouse and conflict in your marriage.
So, my suggestion is for you to bring such issues up at a peace and opportune time (you know such times in your marriage). Suggest solutions and offer to help (never compare your spouse with another person dealing with similar issue), be available to help whether that be cheering on (with sweet nothings) or whatever is needed to help deal with it.
In my experience, such issues are often deeply rooted in nurturing (some times sub-conscious assimilation) and needs delicate transformation of the mind (with God’s word, godly counseling and an encouraging spouse).